RNA interference
RNA Interference | Gene Silencing Technique | Nanotechnology and RNAi

RNA interference: RNAi is a gene silencing technology that inhibits protein synthesis in target cells using double-stranded RNA. Same result is achieved by Antisense technology through single-stranded RNA. RNAi technologies are now known to formulate drugs capable of reducing cholesterol levels by half. The technology also finds immense importance in treating acute viral infections like

UMMID
Unique Methods of Management and treatment of Inherited Disorders (UMMID)

UMMID: UMMID stands for Unique Methods of Management and treatment of Inherited Disorders. DBT has started the UMMID Initiative which is designed on the concept of ‘Prevention is better than Cure’. Taking into account the congenital and hereditary genetic diseases are becoming a significant health burden in India, and realizing the need for adequate and

Bio Toilets
What is Bio Toilet and How does it work?

Introduction: Even after 100 years of invention of a flush toilet, today only 15% of people in the world have a flush toilet. You will be surprised to know that only 3% people of rural India and 25% of urban Indians have flush toilets. The Indian government has restricted the practice of manual scavenging since

MANAV: Human Atlas Initiative
MANAV: Human Atlas Initiative

Introduction: For the first time, Indian scientists will be mapping every single tissue of the human body to have a deeper understanding of the roles of tissues and cells linked to various diseases. The Department of Biotechnology (DBT) launched MANAV: Human Atlas Initiative towards improving knowledge on human physiology. About the project: It is a

3 Parent Babies
3 Parent Babies

Introduction: The ‘Three Parent Baby’ mechanism involves the replacement of a small amount of faulty DNA in a mother’s egg with healthy DNA from a second woman. This results in the baby inheriting genes from two mothers and one father. The idea is to prohibit certain genetic diseases being passed on to children. In simple

Biological data storage, Access and sharing policy of India
Biological data storage, Access and sharing policy of India

Introduction: To define guidelines for sharing of data generated by scientists in India using modern biotechnological tools and methods, DBT has issued the ‘Biological data storage, access and sharing policy of India’. Need to have a policy in place: Advances in DNA sequencing and other high-throughput technologies have enabled government agencies to fund research towards

Denisovans
Denisovans

Introduction: Scientists have uncovered the most complete remains yet from the mysterious ancient-hominin group known as the Denisovans. The jawbone, discovered high up on the Tibetan Plateau and dated to more than 160,000 years ago, is also the first Denisovan specimen found outside the Siberian cave in which the hominin was uncovered a decade ago

Tardigrade
Tardigrade

Introduction: On April 11, 2019 the Israeli spacecraft Beresheet attempted to land on the Moon, but crashed on the surface. It was carrying a number of items — including thousands of specimens of a living organism called Tardigrade. Tardigrade: The Tardigrade, also known as water bear, is among the toughest and most resilient creatures on

Proton therapy
Proton Therapy

Introduction: Recently, Apollo hospital group installed South Asia’s first proton therapy centre at its Chennai hospital. Proton therapy, also called proton beam therapy, is a type of radiation therapy. It uses protons rather than x-rays to treat cancer. A proton is a positively charged particle. A t high energy, protons can destroy cancer cells. Doctors

Nobel Prize for Physiology or Medicine (2019)
Nobel Prize for Physiology or Medicine (2019)

Introduction: The Nobel Prize for Physiology or Medicine 2019 was jointly awarded to William G. Kaelin, Sir Peter J. Ratcliffe, and Gregg L. Semenza, for ‘their discoveries on how cells sense and adapt to oxygen availability.’ The discovery by scientists aims to identify the molecular machinery that regulates the activity of genes in response to

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